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Tuesday, May 5, 2020 | History

5 edition of Carcinogenic and Chronic Toxic Hazards of Aromatic Amines found in the catalog.

Carcinogenic and Chronic Toxic Hazards of Aromatic Amines

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Published by Elsevier Pub. Co. in Amsterdam, New York .
Written in English


Edition Notes

SeriesElsevier monographs on toxic agents, v.26, Edited by E. Browning
The Physical Object
Pagination208 s.
Number of Pages208
ID Numbers
Open LibraryOL24779371M
OCLC/WorldCa475697265

Biogenic amines are low molecular weight organic nitrogen compounds. They are formed by the decarboxylation of amino acids or by amination and transamination of aldehydes and ketones during normal metabolic processes in living cells and therefore are ubiquitous in animals, plants, microorganisms, and humans. In food and beverages, they are formed by the enzymes of raw Author: Dincer Erdag, Oguz Merhan, Baris Yildiz. Carcinogenic Potential: None listed in OSHA, NTP or ACGIH; IARC Group 2B (limited evidence for carcinogenicity in humans). Target Organs: 2,4-D: Skin, CNS, liver, kidneys ECOLOGICAL INFORMATION This product is toxic to fish and aquatic invertebrates. Book Review IARC Monographs: The Evaluation of Carcinogenic Risk of Chemicals to Man. Volume 4: Some Aromatic Amines, Hydrazine and Related Substances, N-Nitroso Compounds and Miscellaneous Alkylating Agents, Volume 5: Some Organochlorine Pesticides, Assessment of the Carcinogenicity and Mutagenicity of Chemicals: Report of a WHO Scientific GroupCited by: 2. Aromatic amines form fluorescent products just as the aliphatics do, but the aromatic products are unstable. However, the parent compounds do form stable yellow derivatives. Rinde and Troll () used Fluram to develop a colorimetric procedure to .


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Carcinogenic and Chronic Toxic Hazards of Aromatic Amines by T. S. Scott Download PDF EPUB FB2

Carcinogenic and chronic toxic hazards of aromatic amines. Amsterdam, New York, Elsevier Pub. [sole distributors for the U.S.: American Elsevier Pub. Co., New York] (OCoLC) Document Type: Book: All Authors / Contributors: Thomas Smith Scott.

Carcinogenic and Chronic Toxic Hazards of Aromatic Amines [T.S. Scott] on *FREE* shipping on qualifying by:   For personal accounts OR managers of institutional accounts. Username *. Password *Author: R.

Schoental. Book: Carcinogenic and Chronic Toxic)EIazards of Aromatic Amines. + pp. Abstract: The title Carcinogenic and Chronic Toxic Hazards of Aromatic Amines book a reminder that occupational tumour of the bladder bladder Subject Category: Anatomical and Morphological StructuresCited by: Laboratory Decontamination and Destruction of Carcinogens in Laboratory Wastes: Some Aromatic Amines and 4-Nitrobiphenyl (I a R C Scientific Publication) by n/a and a great selection of related books, art and collectibles available now at Acute and chronic toxicity of aromatic Carcinogenic and Chronic Toxic Hazards of Aromatic Amines book studied in the isolated perfused rat liver.

Ambs S(1), Neumann HG. Author information: (1)Department of Toxicology, University of Würzburg, Germany. Isolated perfused livers from male Wistar rats were used to study acute and chronic toxic effects of carcinogenic aromatic by: Dobriner K, Hogmann K, Rhoads CP.

THE METABOLISM OF beta-NAPHTHYLAMINE BY RATS, RABBITS AND MONKEYS. Science. Jun 20; 93 ()– [MANSON LA, YOUNG L. Biochemical studies of toxic agents; the metabolism of 2-naphthylamine and 2-acetamidonaphthalene. of the aromatic amines In our first QSAR analysis of the carcinogenic-ity of the aromatic amines, we considered only the carcinogenic aromatic amines, and we investigated the structural factors that Carcinogenic and Chronic Toxic Hazards of Aromatic Amines book the gradation of carcinogenic potency in rodents [9].

The study fo-cused on the homogeneous class of non-heterocyclic Size: KB. Aromatic amines are aromatic hydrocarbons with amino substituents that usually appear during the thermal treatment of foods with high protein content.

These aromatic amines are also used in dyes, as antioxidants, and as precursors of pharmaceutical products. Figure summarizes the main biotransformation routes of 2-aminonaphthalene.

This chemical can be initially. These observations have since been followed by the identification of the carcinogenic potential of other aromatic amines in humans and animal models, such.

Abstract. Many polycyclic aromatic amines Carcinogenic and Chronic Toxic Hazards of Aromatic Amines book mutagenic, and their genotoxic properties are held responsible for their biological effects.

The genotoxic effects are explained by the formation of metabolites that react with macromolecules by forming adducts (Kriek ; Franz et al. ).Cited by: 5.

Aromatic amines are found in industries such as iron, steel, dyes, pharmaceuticals, oil refining, personal household services, textile manufacturing, leather manufacturing, and rubber.

[4], [5] They are also found in tobacco smoke, well-cooked meat, hair dye and diesel exhaust and can be produced by burning wood chips. Aromatic amines also cause bladder cancer whenever they are tested in dogs.

The Working Group identified several additional aromatic amines that are carcinogenic to human beings. ortho-Toluidine is used in the production of dyes, pigments, and rubber chemicals, and as a. Heterocyclic amines (HCAs) and polycyclic aromatic hydrocarbons (PAHs) are chemicals formed when muscle meat, including beef, pork, fish, or poultry, is cooked using high-temperature methods, such as pan frying or grilling directly over an open flame (1).

In laboratory experiments, HCAs and PAHs have been found to be mutagenic—that is, they. Sorry, our data provider has not provided any external links therefor we are unable to provide a : R. Schoental. Clayson () suggested that, to be carcinogenic, an aromatic amine had to: o poseese two or three con fidgeted aromatic ring systems {~.g., biptleny} or napbthalene) and o have the amino group substituted in the aromatic ring in the pare position to a conjugated aromatic system.

his suggestion has been refined more recently by the clear. Aromatic amines are widely used in dyeing industry as a starting material for manufacturing of different types of azo dyes, such as methyl orange, sunset yellow, ponceau colors.

As aromatic amines take part in many chemical reactions, they are used in chemical industry, for example for manufacturing of petrol and diesel fuel, varnishes, and. carcinogenic and chronic toxic hazards of aromatic amines— By Mitchell R.

Zavon Topics: Journal Departments: Book ReviewsAuthor: Mitchell R. Zavon. Azo dyes are widely used in the food, pharmaceutical, cosmetic, textile and leather industries.

They can be reduced by azoreductases in intestinal bacteria, liver cells and skin surface microflora so that aromatic amines are released. In this study an analytical system for the determination of carcinogenic aromatic amines at the picogram to femtogram level and a Cited by: Over 5, different chemicals are used in hair dye products, some of which are reported to be carcinogenic (cancer-causing) in animals (2–4).

Because so many people use hair dyes, scientists have tried to determine whether exposure to the chemicals in hair coloring products is associated with an increased risk of cancer in people. Isolated perfused livers from male Wistar rats were used to study acute and chronic toxic effects of carcinogenic aromatic amines.

We investigated the hypothesis that aromatic amines can generate reactive oxygen species as part of their by: Suggested Citation:"Carcinogenic Potency and Risk Estimation."National Research Council. Aromatic Amines: An Assessment of the Biological and Environmental gton, DC: The National Academies Press.

doi: / IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man: Some Aromatic Amines, Hydrazine and Related Substances, N-nitroso Compoundsand Miscellaneous Alkylating Agents.

Vol 4 and a great selection of related books, art. A carcinogen is any substance, radionuclide, or radiation that promotes carcinogenesis, the formation of may be due to the ability to damage the genome or to the disruption of cellular metabolic processes.

Several radioactive substances are considered carcinogens, but their carcinogenic activity is attributed to the radiation, for example gamma rays and alpha. Abstract. Aromatic amines (arylamines) such as o-toluidine, 2-aminonaphthalene, and 4-aminobiphenyl occur in the environment and are constituents of tobacco exposure to these aromatic amines has long been associated with an Cited by:   Aromatic amines are a class of organic compounds that include many members that are carcinogenic, both experimentally in the research setting and experientially in human life.

The carcinogenesis literature documents innumerable studies demonstrating that administration of a considerable variety of aromatic amines to experimental animals of Cited by: Aromatic amines are widely used as precursor to pesticides, pharmaceuticals, and dyes. Aromatic amines in textiles.

Since Augustthe new standard EN Textiles - Methods for determination of certain aromatic amines derived from azo colorants - Part 1: Detection of the use of certain azo colorants accessible with and without extracting the fibres is effective.

Current Toxicology Series Series Editors Diana Anderson Tno Bibra International Ltd, Surrey, UK Michael D Waters Consultant, Chapel Hill, NC, USA Timothy C Marrs Department of Health, London, UK Food Borne Carcinogens Heterocyclic Amines Edited by Minako Nagao, Tokyo University of Agriculture, Japan Takashi Sugimura, National Cancer Center, Japan Food Cited by: Primary aromatic amines from printed food contact materials such as napkins or bakery bags BfR Opinion No / of 24 July Some substances in the group of primary aromatic amines (PAAs) are carcinogenic.

PAAs can, for example, occur as contaminants in colour pigments. They can pose a health risk in. Quantitative Structure−Activity Relationships of Mutagenic and Carcinogenic Aromatic Amines Article in Chemical Reviews (10) November with. A new method of separation of carcinogenic aromatic amines in wastewater is given.

With SDS (C12H25O4SNa) and β-CD (β-cyclodextrin) addition, it is effective to improve separation. At the same time, it forms mixed micelle. As a result, a micellar electrokinetic capillary chromatography (MECC) system was established.

Nine aromatic amines were. Suggested Citation:"Metabolism of Aromatic Amines."National Research Council. Aromatic Amines: An Assessment of the Biological and Environmental gton, DC: The National Academies Press. doi: / A report on a survey of the presence of aromatic amines in textiles that are in direct and prolonged contact with the skin or the mouth.

The survey is a follow-up to a similar larger survey conducted in Certain azo dyes used to dye textiles can reduce to carcinogenic aromatic amines, including benzidine. T1 - Methemoglobin Formation and Characterization of Hemoglobin Adducts of Carcinogenic Aromatic Amines and Heterocyclic Aromatic Amines.

AU - Pathak, Khyatiben V. AU - Chiu, Ting Lan. AU - Amin, Elizabeth Ambrose. AU - Turesky, Robert J. PY - /3/ Y1 - /3/21Cited by: NIOSHTIC-2 Publications Search. Search NIOSHTIC Advanced Search Search Help About NIOSHTIC-2 Feedback.

Metabolism of Azo Dyes to Potentially Carcinogenic Aromatic Amines. Authors Nony-CR Source National Center for Toxicological Research, Jefferson, Arkansas Mar pages. Scott has written: 'Carcinogenic and chronic toxic hazards of aromatic amines' Asked in Authors, Poets, and Playwrights What has the author Joseph Marvin Greendorfer written.

The NICNAS proposals for listing all the specified aromatic amines in Schedule 7 and/or Sched is to capture their use in dyes that may be metabolised to the listed aromatic amines. All are alleged to have genotoxic and/or carcinogenic properties. Scott has written: 'Carcinogenic and chronic toxic hazards of aromatic amines' Asked in Authors, Poets, and Playwrights What has the author Merit Scott written.

T1 - Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon. AU - Turesky, Robert J. AU - Lang, Nicholas P. AU - Butler, Mary Ann. AU - Teitel, Candee H. AU - Kadlubar, Fred F.

PY - /10/1. Y1 - /10/1Cited by: Conference proceedings; Book: IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans Vol pp pp. Abstract: This publication represents the views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, which met in Lyon, June.

The group of primary aromatic amines consist of compounds with an amine and pdf aromatic hydrocarbon. The simplest structure is amino benzene, also called aniline.

Since some of the PAA compounds, e.g. 2-naphtylamine, toluidine and anisidine are classified as carcinogenic, they should not be present in food.Carcinogenic and Chronic Toxic Hazards of Aromatic Amines.

ByT. S. Scott. (Pp. ; 50figures +20tables. 15) Amsterdam: Elsevier. This monograph is composed of three parts. In the first is given the historical background, the chemical structures and uses of aromatic amines in industry, the acuteandchroniclesions theyproduce,andthe Author: R.

Schoental.Aniline is a weak base. Aromatic amines such ebook aniline are, in general, much weaker bases than aliphatic amines because of the electron-withdrawing effect of the phenyl group. Aniline reacts with strong acids to form anilinium (or phenylammonium) ion (C6H5-NH3+).